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The arrangement and contractility of myofibrills and collagen fibers may be altered leading to deterioration in plasticity. Indeed, to experience optimal bodybuilding progress we must create enough muscle micro-trauma to signal the repair process which, in turn, will, if enough of the right nutrients have been supplied, and sufficient rest has been achieved, prompt a compensatory effect resulting in larger muscles.
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Chandler and Blair23 compared the effects of amphetamines and placebo in six recreationally trained athletes and found significant improvements in knee extension strength, sprint acceleration, and anaerobic capacity.
There are, however, significant potential adverse effects regarding its use that can be best understood by studying known growth hormone excess, as demonstrated in the acromegalic syndrome. Synthetic androgens were born in the 1930s when Foss first described the medical use of orally bioavailable methyltestosterone. The use of multiple drugs greatly increases side effects and risks to the user. At present, more Americans utilize Dianabol than any other type of steroid, except for testosterone.
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